Breastfeeding after breast cancer in young BRCA carriers

E Blondeaux; V Delucchi; E Mariamidze; R Bernstein-Molho; S Frank; A Ferrari; S Linn; HJ Kim; E Agostinetto; S Paluch-Shimon; L Cortesi; A Di Meglio; J Balmana; R Yerushalmi; KA Rodriguez-Wallberg; T Renaud; W Cui; HCF Moore; SM Wong; K Pogoda; M Lustberg; KA Phillips; S Han; F Puglisi; C Vernieri; J Bajpai; A Sonnenblick; C Rousset-Jablonski; L De Marchis; U De Giorgi; G Bianchini; L Texeira; FP Duhoux; C Villarreal-Garza; V Sini; R Fruscio; L Del Mastro; I Demeestere; HA Azim; FA Peccatori; AH Partridge; M Lambertini

Journal article

Breastfeeding after breast cancer in young BRCA carriers

E Blondeaux, V Delucchi, E Mariamidze, R Bernstein-Molho, S Frank, A Ferrari, S Linn, HJ Kim, E Agostinetto, S Paluch-Shimon, L Cortesi, A Di Meglio, J Balmana, R Yerushalmi, KA Rodriguez-Wallberg, T Renaud, W Cui, HCF Moore, SM Wong, K Pogoda Show all

Journal of the National Cancer Institute | Published : 2025

DOI: 10.1093/jnci/djaf177

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Abstract

Background We investigated safety of breastfeeding after breast cancer in patients carrying germline BRCA pathogenic or likely pathogenic variants. Methods This was an international, multicenter, hospital-based, retrospective cohort study including BRCA carriers diagnosed with stage I-III invasive breast cancer at age 40 years or younger between January 2000 and December 2020 (NCT03673306). Locoregional recurrences and/or contralateral breast cancers, disease-free survival (DFS), and overall survival (OS) were compared between patients who breastfed after delivery and those who did not. Results Among 4732 patients included from 78 centers worldwide, 659 had a pregnancy after breast cancer di..

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University of Melbourne Researchers

Wanyuan Cui Author

Kelly Phillips Author

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Keywords

Prevention

Breast Cancer

3211 Oncology and Carcinogenesis

Women'S Health

3 Good Health and Well Being

Cancer

Nutrition

Breastfeeding, Lactation and Breast Milk

32 Biomedical and Clinical Sciences